Assistant Professor Education: B.Sc., Chemistry, University of Southampton, Southampton, UK (1995); Ph.D., Chemistry, University of Glasgow, Glasgow, UK (1999) Awards: Royal Society University Research Fellowship (2001-2004) Email: Email: Paul.Blakemore@science.oregonstate.edu Office: Gilbert Hall 351 Phone: (541) 737-6728 Fax: (541) 737-2062 Research Group Website: http://www.chemistry.oregonstate.edu/blakemore/ Organic & Bioorganic web site: http://www.chemistry.oregonstate.edu/organic/

Research within the Blakemore Research Group is focused on the development of new methods and concepts for stereoselective synthesis.  Emphasis is placed on the following three areas: (a) study of novel axially chiral ambifunctional molecules with applications in catalysis, (b) development of the stereospecific reagent controlled homologation (StReCH) process as a unified reductionist synthetic paradigm, and (c) practical total synthesis of important alkaloid targets (e.g., sparteine, thebaine).

Representative Publications

• Enzymatic Resolution of 7,7´-Dihydroxy-8,8´-biquinolyl Dipentanoate and Its Conversion to 2,2´-Di-tert-butyl-7,7´-dihydroxy-8,8´-biquinolyl, J. Org. Chem., 2007, 72 (24), 9368-9371.
• Iterative Stereospecific Reagent-Controlled Homologation of Pinacol Boronates by Enantioenriched α-Chloroalkyllithium Reagents, J. Am. Chem. Soc., 2007, 129 (11), 3068-3069.
• Resolution, Enantiomerization Kinetics, and Chiroptical Properties of 7,7´-Dihydroxy-8,8´-biquinolyl, J. Org. Chem., 2006, 71 (21), 8212-8218.
• A Practical Synthesis of (±)-α-Isosparteine from a Tetraoxobispidine Core, Org. Lett., 2005, 7 (21), 4721-4724.
• Ethyl (Benzothiazol-2-ylsulfonyl)acetate: A New Reagent for the Stereoselective Synthesis of α,β-Unsaturated Esters from Aldehydes, Org. Biomol. Chem., 2005, 3, 1365-1368.