Carter Research Group
focused on the total synthesis of complex, biologically-active natural products


Welcome

Welcome to the Carter Research Group at Oregon State University. Below and to the right are selected examples of the projects we are currently working on. Click on each molecule for more information.

Please use the links at left to navigate our site.

diers-alder
Amphidinolide Azaspiracid

           siamenol       



Himeradine
selamectin


vacidin
TMC95

News

  • September 23, 2008 - Hua's paper on a practical proline mimetic, N-(p-Dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide (a.k.a. Hua Cat), for catalyzing enantioselective and diastereoselective aldol reactions was published today in Organic Letters (ABSTRACT).
  • August 22, 2008 - Brad's paper on the elucidation of competing tandem [2+2] cycloaddition/[1,3] sigmatropic shift pathway in our biaryl synthesis was published today in the Journal of Organic Chemistry (ABSTRACT).
  • August 20, 2008 - Jo presents her work at the National American Chemical Society meeting in Philadelphia, PA today (ABSTRACT).
  • August 19, 2008 - The Carter laboratory was awarded a Venture Fund grant from Oregon State University entitled "Commercialization of Hua Cat for Use in Asymmetric Chemical Processes." OSU has issue a press release concerning these awards.
  • June 27, 2008 - Hua's enantioselective total synthesis of lycopodine was published today in the Journal of the American Chemical Society (ABSTRACT).
  • June 5, 2008 - Erik, Lauren, Hua and Nathan's paper on an improved protocol for asymmetric, intramolecular heteroatom Michael addition using organocatalysis and its application to the syntheses of homoproline, pelletierine, and homopipecolic acid was published to day in the Journal of Organic Chemistry (ABSTRACT).
  • May 20, 2008 - Liang and Wei's total syntheses of amphidinolide B1 and the proposed structure of amphidinolide B2 were published today in the Journal of the American Chemical Society (ABSTRACT).
  • May 8, 2008 - Johanna Perkins successfully passed her oral preliminary exam today. Congrats to Jo!!
  • April 22, 2008 - Brad successfully defended his Ph.D. dissertation today. He is off to a postdoctoral position in Professor Marcus Tius' laboratory (University of Hawaii) in June. Congrats to Dr. Ashburn!
  • February 26, 2008 - Johanna's paper on the synthesis of Programmable Tetra-ortho Substituted Biaryl Compounds Using Diels-Alder Cycloadditions / Cycloreversions of Di-Substituted Alkynyl Stannane was published in the Journal of the American Chemical Society (ABSTRACT).
  • February 8, 2008 - Hua's article on a Scalable Synthesis of Lissamine Rhodamine B Sulfonyl Chloride and Incorporation of Xanthene Derivatives onto Polymer Supports was published in Synthesis today (ABSTRACT).
  • December 14, 2007 - Mike, Brad and Johanna's article in the Journal of Organic Chemistry is showcased on the cover of Issue 26 of the Jouranl of Organic Chemistry. (ABSTRACT)
  • November 27, 2007 - Brad's communication on the importance of the ortho-nitro moiety in our Diels-Alder Approach to Biaryls (DAB) was published today in Organic and Biomolecular Chemistry (ABSTRACT).
  • Novebmer 12, 2007 - Brad, Lauren and Betsy's full paper on the successful synthesis of the Western biaryl portion of TMC-95 was published in Tetrahedron as a Symposium-in-Print series entitled "Cycloaddition and benzannulation approaches to functionalised aromatic compounds" today (ABSTRACT).
  • September 25, 2007 - An article detailing Professor Carter's successful efforts to raise the funds to purchase a 700 MHz NMR for OSU Chemistry was described in a recent press release from OSU.
  • September 19, 2007 - Professor Carter has been awarded the 2007 Sugihara Young Faculty Research Award. The purpose of the award is to recognize outstanding scholarship in science by honoring a young faculty member in the College of Science at Oregon State University.
  • August 19, 2007 - Brad presents his work at the National American Chemical Society Meeting in Boston, MA.
  • June 29, 2007 - Brad's paper on the synthesis of tetra-ortho-substituted phosphorous- and carbonyl-containing biaryls via a Diels-Alder approach was published in the Journal of the American Chemical Society (ABSTRACT) today.
  • June 29, 2007 - Mike, Brad and Johanna's paper on the synthesis of halogenated biaryl templates via a Diels-Alder approach and its application to the total synthesis of siamenol was published in the Journal of Organic Chemistry (ABSTRACT) today.
  • June 29, 2007 - Brad's paper on the synthesis of tetra-ortho-substituted biaryls containing propargylic tertiary alcohols as dienophiles via a Diels-Alder approach was published in the Journal of Organic Chemistry (ABSTRACT) today.


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