2009 Symposium Program & Presentation Abstracts

Click on presenter names to see abstracts.

medicinal chemistry & chemical biology

09:20: Benjamin Farnell (Univ. of Victoria, BC, Canada. Advisor: Fraser Hof)

Chemical Probes of the Cancer Protein S100A7

09:40: Daniel Collins (Washington State Univ., Pullman, WA. Advisor: Ming Xian)

A New Approach to S-Nitrosothiol Detection

10:00: Eric Standley (Boise State Univ., Boise, ID. Advisor: Eric Brown) *PRIZE WINNER*

Heterocumulenes Inactivate Carbonic Anhydrase: Use of Synthetic Models to Understand the Mechanism of Reactivation

10:20: Joseph Choi (Washington State Univ., Pullman, WA. Advisor: Cliff Berkman)

Sulfonamide Inhibitors of Prostate Specific Membrane Antigen

key-note lecture 1

chair: Tim Clark (WWU)

Prof. Thomas Scanlan (Oregon Heath & Sciences Univ., Portland, OR)

Selective Ligands for Thyroid Hormone Receptors: A Journey from Bench to Bedside

#001: Rachel Feeny (University of Portland, Portland, OR. Advisor: Warren Wood)

Synthesis of Sultam Thioureas: Antiviral Compounds Against West Nile Virus and Japanese Encephalitus Virus

#002: Darrin Flanigan (Oregon State University, Corvallis, OR. Advisor: Paul Blakemore)

Development of a Two-Step Synthesis of 7,7´-Dihydroxy-8,8´-biquinolyl (azaBINOL) from Quinoline

#003: Tyler Law (University of Alaska, Anchorage, AK. Advisor: Marc Perry) *PRIZE WINNER*

N-Heterocyclic Carbenes as Ligands in the Iron-Catalyzed Cross-Coupling of Primary and Secondary Alkyl Grignard Reagents with Unactivated Aryl Chlorides

#004: Justin Pierson (Oregon State University, Corvallis, OR. Advisor: Christopher Beaudry)

Enantioselective Allylation of Nucleophilic Arenes

#005: Andrew Willeford (Oregon State University, Corvallis, OR. Advisor: Christopher Beaudry)

Total Enantioselective Synthesis of 9’-Desmethylgarugamblin 1

13:30: Sean Egan (Univ. of Alaska, Anchorage, AK. Advisor: Marc Perry)

pi-Acidic Ligands in the Iron-Catalyzed Cross-Coupling of N-Aryl Chlorides and Secondary Alkyl Grignard Reagents

13:50: Aaron Johnson (Brigham Young Univ., Provo, UT. Advisor: Steven Castle)

Asymmetric Allylation of Assorted Ketones Using Nakamura's Reagent

14:10: Cameron Moore (Western Washington Univ., Bellingham, WA. Advisor: Timothy Clark)

Cu-Catalyzed Diboration of Ketones: Facile Synthesis of Tertiary alpha-Hydroxy Boronate Esters

14:30: Charlotte Osborne (Willamette University, Salem, OR. Advisor: Andrew Duncan)

Stereocontrolled Organocatalytic Synthesis of Oxacycles

14:50: Erasmus Volz (Western Washington Univ., Bellingham, WA. Advisor: Gregory O'Neil)

Metathesis Reactions of beta-Acyloxysulfones for Polyene Synthesis

15:30: Gabriel Rudebusch (Univ. of Nevada, Reno, NV. Advisor: Ben King)

Linear Acenes by Aryne Addition to a Novel Pyreno[c,f]difuran

15:50: Alexander Natale (Univ. of Idaho, Moscow, ID. Advisor: Richard Williams)

Homoaromaticity in Semibulvalenes

16:10: Nathan Lindquist (Univ. of OR, Eugene, OR. Advisor: Darren Johnson) *PRIZE WINNER*

Co-crystallization of a Self-Assembled Tetranuclear Arsenic(III) Metallacyclophane with Two Diastereomeric Metallcycle Intermediates

key-note speakers Prof. Thomas Scanlan and Dr. Joel Hawkins discuss their career tracks and answer questions from the floor

target directed synthesis

09:20: Bryan Beall (Oregon State Univ., Corvallis, OR. Advisor: Paul Blakemore)

Target Directed Synthesis via Stereospecific Reagent Controlled Homologation: Towards an Elaboration of Pregabalin (Lyrica)

09:40: Joel Hanson (WWU, Bellingham, WA. Advisor: Timothy Clark) *PRIZE WINNER*

Boron-Substituted Analogs of the Shvo Hydrogenation Catalyst:
Applications in Directed C-H Borylations

10:00: Jason Lusk (Oregon State Univ., Corvallis, OR. Advisor: Rich Carter)

Toward Novel Analogues of the Natural Product Siamenol via a Diels-Alder Strategy for Biaryl Formation

10:20: James Woods (Washington State Univ., Pullman, WA. Advisor: Philip Garner)

Synthesis of Quinocarcin Based Inhibitors of Cell Migration

key-note lecture 2

chair: Chris Beaudry (OSU)

Dr. Joel Hawkins (Pfizer Inc., Groton, CT)

Case Studies of Heterocyclic Chemistry Highlighting Flow Chemistry and Reaction Profiling